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ORIGINAL ARTICLE
Year : 2020  |  Volume : 26  |  Issue : 2  |  Page : 175-179

Variation of serum carcinoembryonic antigen with grading and radiological staging in colorectal malignancy


Department of General Surgery, Government Medical College, Kozhikode, Kerala, India

Correspondence Address:
Dr. Akshaya Mohan
Department of General Surgery, Government Medical College, Kozhikode, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ksj.ksj_6_20

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Introduction: Serum carcinoembryonic antigen (CEA) is used universally as a tumour marker for colorectal malignancies. The study aims to compare the serum CEA levels in different histopathological grades and radiological stages and to see if there is a relation between them so that advanced stage can be predicted early with serum CEA level. Methodology: An observational study was done on 101 patients with colorectal malignancies. Pre-operative serum CEA value, radiological staging and pathological grading were compared. Results: Fifty-eight patients were male and 43 female. The mean age was 62.6 years. The mean serum CEA value was 14.99 ng/ml. There was a significant relation between CEA and T staging. There was no significant relation with nodal status or metastases or grading. Conclusion: The study revealed a relationship of higher T staging with CEA. No relationship was found with nodal/metastasis status/grading. We can suspect tumours with advanced T stage clinically, if CEA is elevated in patients with colorectal malignancies.


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