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ORIGINAL PAPER
Year : 2020  |  Volume : 26  |  Issue : 2  |  Page : 167-170

Use of serial monitoring of serum albumin and total leucocyte in predicting septicaemia in burns patients


Department of General Surgery, Government Medical College, Kozhikode, Kerala, India

Correspondence Address:
Dr. Shabin Majeed
Revathy, TKMC P.O., Kollam - 691 005, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ksj.ksj_22_20

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Introduction: The most common complication of burns is infection-producing sepsis. Therefore, it is necessary that septicaemia be diagnosed early. Many biomarkers help to diagnose septicaemia early. Serum albumin levels and total leucocyte counts were commonly measured blood parameters in burn patients. This study was undertaken due to the dearth of information on the role of serum albumin levels and total leucocyte count in the diagnosis of septicaemia. Materials and Methods: This retrospective, correlational study used existing medical record data of 60 patients including the laboratory values admitted in the burns intensive care unit of the department of general surgery during the period January 2017–May 2019 and during the follow-up period. Results: Statistically significant association was observed between low serum albumin values and positive blood culture (P < 0.0001). Mean serum albumin had an excellent predictive validity in predicting blood culture indicated by area under the curve of 0.907. Similarly, septicaemia was correlated with a high total number of leucocytes and a statistically significant correlation (P < 0.0001). In predicting blood culture, mean total leucocyte counts demonstrated excellent predictive validity indicated by area under the curve of 0.985. Conclusion: Serial monitoring of serum albumin and total leucocyte count could be used in burn patients to predict septicaemia.


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